Hepatoprotective Effect of Cornus mas Fruits Extract Against Carbon Tetrachloride-Induced Hepatic Damage in Male Albino Rats
نویسندگان
چکیده
1Liver and Gastrointestinal Diseases Research Center, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IR Iran 2Department of Biology, Faculty of Sciences, University of Tabriz, Tabriz, IR Iran 3Drug Applied Research Center, School of Medicine, Tabriz University of Medical Sciences, Tabriz, IR Iran 4Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, IR Iran
منابع مشابه
P-22: The Effect of Carbon Tetrachloride on Fertility Parameters and Therapeutic Effect of Cornus Mas
Background: Various investigations have established that carbon tetrachloride (CCl4), a clear, colourless, volatile, heavy and nonflammable liquid, causes generation of free radicals in many tissues such as testis. a wide range of side effects such as reproductive toxicity has been observed following the administration of this liquid in experimental animals. Numerous studies have shown that amo...
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Protective action of Ficus carica leaf ethanolic extract (obtained by maceration) was evaluated in an animal model of hepatotoxicity induced by carbon tetrachloride (CCl4). Male albino mice were divided into six groups. group I was normal control group; group II received olive oil (CCl4 solvent), groups III-VI received CCl4. After inducing hepatic damage, group III served as control for CCl4; a...
متن کاملHepatoprotective Effect of Ficus carica Leaf Extract on Mice Intoxicated with Carbon Tetrachloride
Protective action of Ficus carica leaf ethanolic extract (obtained by maceration) was evaluated in an animal model of hepatotoxicity induced by carbon tetrachloride (CCl4). Male albino mice were divided into six groups. group I was normal control group; group II received olive oil (CCl4 solvent), groups III-VI received CCl4. After inducing hepatic damage, group III served as control for CCl4; a...
متن کاملHepatoprotective Effect of Otostegia persica Boiss. Shoot Extract on Carbon Tetrachloride-Induced Acute Liver Damage in Rats
In this study, the hepatoprotective effect of the methanol extract of aerial parts (shoot) from Otostegia persica Boiss (Golder) was investigated against the carbon tetrachloride (CCl4)-induced acute hepatotoxicity in male rats. Liver damage was induced through the oral administration of 50% CCl4 in liquid paraffin (2.5 mL/Kg bw, per os) 60 min after the administration of the methanol extract o...
متن کاملP-108: Reproductive Toxic Effect of Carbon Tetrachloride and Therapeutic Effect of Cornus Mas Fruit Extract on Morphology and Histology of Testis in Rats
Background: Carbon tetrachloride (CCl4), an industrial solvent, is a well-established hepatotoxin. Studies demonstrated that liver is not the only target organ of CCl4 since it causes free radical generation in other tissues such as testis. It has also been reported that exposure to CCl4 induces acute and chronic reproductive toxicity. Diverse medicinal plants have been screened and assessed fo...
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